Atypical Complications of Huntington Chorea Disease
نویسندگان
چکیده
منابع مشابه
Huntington chorea presenting with motor neuron disease.
BACKGROUND There have been a few case reports of motor neuron disease in association with Huntington disease (HD). OBJECTIVE To describe a patient presenting with prominent fasciculations, chorea, and possible amyotrophic lateral sclerosis (ALS) in whom genetic testing revealed HD mutation. DESIGN Case report. SETTING University of Texas Southwestern Medical Center, Dallas. Patient A 69-...
متن کاملUpper facial chorea in Huntington disease
To provide a systematic description of component movements of upper facial chorea in Huntington disease, consecutive videos of 25 active patients with confirmed diagnosis were scored on eye opening, eye closing, and procerus/corrugator contractions. Of the 25 patients evaluated, 76% exhibited intermittently widened palpebral fissures associated with frontalis contractions. Brief periods of repe...
متن کاملTetrabenazine as anti-chorea therapy in Huntington Disease: an open-label continuation study. Huntington Study Group/TETRA-HD Investigators
BACKGROUND Tetrabenazine (TBZ) selectively depletes central monoamines by reversibly binding to the type-2 vesicular monoamine transporter. A previous double blind study in Huntington disease (HD) demonstrated that TBZ effectively suppressed chorea, with a favorable short-term safety profile (Neurology 2006;66:366-372). The objective of this study was to assess the long-term safety and effectiv...
متن کاملonset in Huntington ' s chorea . Affected parent and age of
In a recent report, Merritt et al. (1969) searched the literature and their own material for cases of Huntington's chorea with onset before the age of 21. They found that when the disease began in childhood or adolescence the history was generally on the father's side. In 89 out of 113 cases in which descent could be determined, the father or his relatives were affected. The sex ratio among the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cardiovascular Pharmacology: Open Access
سال: 2016
ISSN: 2329-6607
DOI: 10.4172/2329-6607.1000188